Shopping Cart
- Remove All
Your shopping cart is currently empty
Ibiglustat (L-Malic acid)
Ibiglustat (L-Malic acid) (Ibiglustat L-Malic acid) is a selective, brain-penetrant, and allosteric inhibitor of glucosylceramide synthase. Ibiglustat (L-Malic acid) can be used in studies about PD Parkinson’s disease, SRT in Fabry’s and Gaucher’s.
Catalog No. T11599Cas No. 1629063-78-0
Select Batch
Purity:99.79%
Contact us for more batch information
Ibiglustat (L-Malic acid)
Catalog No. T11599Alias Ibiglustat L-Malic acid, GZ402671 (L-Malic acid), Venglustat (L-Malic acid), SAR402671 (L-Malic acid)Cas No. 1629063-78-0
Ibiglustat (L-Malic acid) (Ibiglustat L-Malic acid) is a selective, brain-penetrant, and allosteric inhibitor of glucosylceramide synthase. Ibiglustat (L-Malic acid) can be used in studies about PD Parkinson’s disease, SRT in Fabry’s and Gaucher’s.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $33 | In Stock | |
| 5 mg | $93 | In Stock | |
| 10 mg | $137 | In Stock | |
| 25 mg | $232 | In Stock | |
| 50 mg | $345 | In Stock | |
| 100 mg | $493 | In Stock | |
| 200 mg | $687 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $107 | In Stock |
Bulk & Custom
Add to Cart
Questions
View MoreInhibitors Related to "Ibiglustat (L-Malic acid)"
Entacapone
OR-611
T2216130929-57-6
Entacapone (OR-611) is a selective and reversible inhibitor of catechol-O-methyltransferase (COMT).
- $30
Size
QTY
Serotonin hydrochloride
Cited
5-HT hydrochloride, 5-HT HCl, Serotonin HCl, 5-Hydroxytryptamine hydrochloride
T2209153-98-0
Serotonin hydrochloride (Serotonin HCl) is an endogenous 5-HT receptor agonist, a monoamine neurotransmitter in the CNS, and a catechol O-methyltransferase (COMT) inhibitor(Ki=44 μM).
- $30
Size
QTY
CitedRisedronic Acid
Risedronate
T0379105462-24-6
Risedronic Acid (Risedronate), a pyridinyl biphosphonate, can inhibit osteoclast-mediated bone resorption.
- $30
Size
QTY
Flopropione Cited
Phloropropiophenone
T05252295-58-1
Flopropione (Phloropropiophenone), a spasmolytic or antispasmodic agent, is used as a 5-HT1A receptor antagonist.
- $30
Size
QTY
CitedAlendronate sodium hydrate
G-704650, Alendronate, MK 217, Alendronate sodium trihydrate, G-704650 Adronat, Fosamax
T6373121268-17-5
Alendronate sodium hydrate (MK 217) is a nitrogen-containing bisphosphonate, which is an effective inhibitor of bone resorption. It is utilized for the treatment and prevention of osteoporosis.
- $40
Size
QTY
OU749
T22128519170-13-9
OU749 is a γ-glutamyl transferase (GGT) inhibitor with an intrinsic Ki of 17.6 μM.
- $42
Size
QTY
Ibandronate sodium
Boniva, Ibandronate sodium salt, Bondronat
T1599L138844-81-2
Ibandronate sodium (Boniva) is a synthetic nitrogen-containing bisphosphonate, used for the treatment of osteoporosis.
- $76
Size
QTY
Risedronate Sodium Cited
NE 58095 Sodium, Risedronic Acid Sodium
T1041115436-72-1
Risedronate Sodium (NE 58095 Sodium) is an aminobisphosphonate derivative of etidronic acid and CALCIUM CHANNEL BLOCKER that inhibits BONE RESORPTION and is used for the treatment of OSTEOPOROSIS.
- $30
Size
QTY
Cited3-Methoxybenzamide
3-MBA
T74395813-86-5
3-Methoxybenzamide (3-MBA) is a competitive inhibitor of poly(ADP-ribose) synthetase.
- $30
Size
QTY
Testosterone propionate
T041957-85-2
Testosterone Propionate is a short acting oil-based injectable formulation of testosterone. Testosterone inhibits gonadotropin secretion from the pituitary gland and ablates estrogen production in the ovaries, thereby decreasing endogenous estrogen levels.
Inquiry
Minodronic acid monohydrate
T8489155648-60-5
Minodronic acid monohydrate is an farnesyl diphosphate synthase inhibitor that acts as a bone resorption inhibitor.
- $30
Size
QTY
(E)-Daporinad
Cited
Daporinad, (E)-N-[4-(1-BENZOYL-PIPERIDIN-4-YL)-BUTYL]-3-PYRIDIN-3-YL-ACRYLAMIDE, APO866, FK866
T2644658084-64-1
(E)-Daporinad (FK866) is a highly specific, non-competitive small molecule inhibitor of nicotinamide phosphoribosyltransferase (NAMPT) with potential anti-tumor and anti-angiogenic activities with an IC50 value of 0.09 nM.
- $36
Size
QTY
CitedProduct Introduction
Bioactivity
Chemical Properties
| Description | Ibiglustat (L-Malic acid) (Ibiglustat L-Malic acid) is a selective, brain-penetrant, and allosteric inhibitor of glucosylceramide synthase. Ibiglustat (L-Malic acid) can be used in studies about PD Parkinson’s disease, SRT in Fabry’s and Gaucher’s. |
| In vitro | Ibiglustat (L-Malic acid) (1 μM) treated Fabry disease cells are close to the physiological level in untreated WT cells in GL-3 levels. Ibiglustat (L-Malic acid) prevents additional GL-3 accumulation and ameliorates the abundant GL-3 levels in FD cardiomyocytes[4]. |
| Alias | Ibiglustat L-Malic acid, GZ402671 (L-Malic acid), Venglustat (L-Malic acid), SAR402671 (L-Malic acid) |
| Molecular Weight | 523.57 |
| Formula | C24H30FN3O7S |
| Cas No. | 1629063-78-0 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 90 mg/mL (171.9 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
| ||||||||||||||||||||||||||||||||||||
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: buy Ibiglustat (L-Malic acid) | purchase Ibiglustat (L-Malic acid) | Ibiglustat (L-Malic acid) cost | order Ibiglustat (L-Malic acid) | Ibiglustat (L-Malic acid) chemical structure | Ibiglustat (L-Malic acid) in vitro | Ibiglustat (L-Malic acid) formula | Ibiglustat (L-Malic acid) molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.